The 18th Annual Scientific Meeting of the Australian & New Zealand Bone & Mineral Society

SESSION 1 - ANZBMS / ESA JOINT SYMPOSIUM
at the Melbourne Exhibition & Convention Centre, La Trobe Theatre

Steroid Hormones and Bone

Chairs: John Eisman, Richard Prince

• Osteoporosis genomewide association studies – hope, hype and how to go forward from here (62KB)
  Brown, M.A. (Australia)
• Bisphosphonates in osteoporosis, benefits and risks (62KB)
  Ebeling, P. (Australia)
• Estrogen mediate osteoprotective effects by controlling osteoclast life cycle (73KB)
  Kato, S., Imai, Y. and Nakamura, T. (Japan)
• Osteoporosis therapeutics, current and future developments (68KB)
  Bilezikian, J. (USA)

SERVIER SYMPOSIUM (with lunch)
at the Melbourne Exhibition & Convention Centre,
Corryong Rooms 4/5
(Includes a boxed lunch provided to attendees)

Chair: Philip Sambrook

• Protos in postmenopausal osteoporosis - what's new?
  John Wark
• Why consider OP treatments for OA?
  Graeme Jones

SESSION 2 - Invited Speakers

Cellular Interactions

Chairs: Evange Romas, Michelle McDonald

• Building new bone: does the osteoblast do all the work? (71KB)
  Petitt, A.R., Alexander, K.A., Chang, M.K. and Raggatt, L.J. (Australia)
• The bone microenvironment and myeloproliferative disease (70KB)
  Purton, L. (Australia)
• Fat and bone: an odd couple (59KB)
  Duque, G. (Australia)

SESSION 3 - Invited Speakers

Basic Biology

Chairs: Natalie Sims, David Findlay

• A non-canonical Wnt signal induces osteoblastogenesis through attenuating PPARgamma-mediated adipogenesis (74KB)
  Kato, S. and Takada, I. (Japan)
• Stress fracture pathophysiology (60KB)
  Schaffler, M.B. (USA)

SESSION 4 - Invited Speakers

Bone Strength

Chairs: Jill Cornish, Nick Fazzalari

• The osteocyte - the cell within (58KB)
  Findlay, D.M. and Atkins, G.J. (Australia)
• Osteocytes and bone remodeling - they’re just dying to do the job (61KB)
  Schaffler, M.B. (USA)
• Skeletal adaptations during growth: insights from animal models (61KB)
  Forwood, M. (Australia)

SESSION 5 - Invited Speakers

Treatment - Osteoporosis

Chairs: Ian Reid, Craig Munns

• Determination of absolute risk and treatment recommendations for osteoporosis (61KB)
  Eisman, J.A. (Australia)
• Osteoporosis in men (68KB)
  Ebeling, P. (Australia)
• Is there value in Ca/Vitamin D supplementation? (56KB)
  Seibel, M. (Australia)

Outstanding Abstracts

• CLINICAL:
  Zoledronate suppresses bone turnover for at least 2 years; a randomized, acebo-controlled trial (92KB)
  Grey, A., Bolland, M., Horne, A., Wattie, D., Gamble, G. and Reid, I.R
• BASIC:
  Transgenic expression of human FSH in female mice has an anabolic effect on bone (82KB)
  Kalak, R., Allan, C.M., McTavish, K.J., Dunstan, C.R., Zhou, H., Handelsman, D.J. and Seibel, M.J.

SANOFI-AVENTIS / PROCTER & GAMBLE SYMPOSIUM
13:00-14:00

Chair: Ego Seeman (Australia)

• Keynote Address:
  Differences in the mechanism of action of bisphosphonates: clinical significance and new insights from the OPTAMISE study
  John Bilezikian (USA)

INVITED PRESENTATION

Chair: Philip Sambrook

• Vitamin D endocrine system and cancer
  Bouillon, R.s

SESSION 7 - Invited Speakers

New Insights into Bone Biology

Chairs: Jack Martin, Colin Dunstan

• Review of computational modeling in bone biology: from intracellular signaling to tissue level (76KB)
  Smith, D.W. and Pivonka, P. (Australia)
• Theoretical investigation of the role of the RANK-RANKL-OPG system in bone remodeling (83KB)
  Pivonka, P., Zimak. J., Smith, D.W., Gardiner, B.S., Dunstan, C.R., Sims, N.A., Martin, T.J. and
  Mundy, G.R. (Australia and USA)
• Cortical Bone: forgotten frontier (47KB)
  Zebaze, R. (Australia)

SESSION 8 - Invited Speakers

Other Metabolic Diseases

Chairs: Sol Posen, Rebecca Mason

• Primary hyperparathyroidism: new concepts, new insights, new guidelines (72KB)
  Bilezikian, J. (USA)
• Management of patients with Pagets (69KB)
  Cundy, T. (New Zealand)
• Treatment of rheumatoid arthritis (61KB)
  Romas, E. (Australia)

MERCK, SHARP & DOHME SYMPOSIUM
13:00-14:00

Chair: Peter Ebeling

• Vitamin D – the latest evidence
  Roger Bouillon (USA)
• Duration of bisphosphonate therapy
  Peter Ebeling (Australia)