Program

The ANZBMS scientific program will run for three days from Thursday 28 to Saturday 30 August 2008. This meeting coincides with the end of the Endocrine Society of Australia (ESA) meeting at the Melbourne Exhibition & Convention Centre. Our meeting will start there with a joint session with ESA at 10:00am Thursday 28 August. Delegates attending that session will then make their way to the main venue at the Hilton On The Park.
Two concurrent 'Meet The Professor' sessions will start early with breakfast at 7.00am Friday 23 August. Seats are limited, the cost is $30 and includes breakfast, book when you register.
The OA/ANZBMS Clinical Update Day will be held on Wednesday 27 August 2008, the day before the ASM at the same venue (Hilton On The Park). See the Satellite Meetings page for program and registration details.
A number of social events have been organised, see the Social Events page for details.

Scientific Program

Key Speakers

Prof John Bilezikian

Chief, Division Endocrinology, Columbia University College of Physicians and Surgeons, New York, USA

Interest: Osteoporosis and PTH action

Prof Mitchell B. Schaffler

Director of Orthopaedic Research, Mount Sinai School of Medicine, USA

Interest: Ultrastructure of
bone and the role of the osteocyte
in control of bone biology.

Open printer-friendly version of program with all days shown

This program will be updated over the coming months. Last updated: 4 September 2008

Thursday, 28 August 2008

09:30	Registration opens at the Melbourne Exhibition & Convention Centre
10:00	SESSION 1 - ANZBMS / ESA JOINT SYMPOSIUM at the Melbourne Exhibition & Convention Centre, La Trobe Theatre Steroid Hormones and Bone Chairs: John Eisman, Richard Prince Osteoporosis genomewide association studies – hope, hype and how to go forward from here (62KB) Brown, M.A. (Australia) Bisphosphonates in osteoporosis, benefits and risks (62KB) Ebeling, P. (Australia) Estrogen mediate osteoprotective effects by controlling osteoclast life cycle (73KB) Kato, S., Imai, Y. and Nakamura, T. (Japan) Osteoporosis therapeutics, current and future developments (68KB) Bilezikian, J. (USA)
12:30	SERVIER SYMPOSIUM (with lunch) at the Melbourne Exhibition & Convention Centre, Corryong Rooms 4/5 (Includes a boxed lunch provided to attendees) Chair: Philip Sambrook Protos in postmenopausal osteoporosis - what's new? John Wark Why consider OP treatments for OA? Graeme Jones	Registration desk opens (12:00), Lunch and Exhibition opens (12:30) at the Hilton On The Park
13:30	Shuttle transfer or delegates make their own way to the Hilton On The Park for the remainder of the ASM
14:00	SESSION 2 - Invited Speakers Cellular Interactions Chairs: Evange Romas, Michelle McDonald Building new bone: does the osteoblast do all the work? (71KB) Petitt, A.R., Alexander, K.A., Chang, M.K. and Raggatt, L.J. (Australia) The bone microenvironment and myeloproliferative disease (70KB) Purton, L. (Australia) Fat and bone: an odd couple (59KB) Duque, G. (Australia)
15:30	Refreshements - Afternoon Tea
16:00	SESSION 3 - Invited Speakers Basic Biology Chairs: Natalie Sims, David Findlay A non-canonical Wnt signal induces osteoblastogenesis through attenuating PPARgamma-mediated adipogenesis (74KB) Kato, S. and Takada, I. (Japan) Stress fracture pathophysiology (60KB) Schaffler, M.B. (USA)
18:00	Welcome Reception Cocktail Party and Exhibition

Friday, 29 August »

Friday, 29 August 2008

07:00

Registration desk opens

Concurrent Sessions:

Meet The Professor 1.

Prof John Bilezikian:

Management and diagnosis of osteoporosis

Prof Bilezikian is Chief, Division Endocrinology, Columbia University College of Physicians and Surgeons, New York, USA

Seats are limited, cost is $30 (includes breakfast). Book when you register.

Meet The Professor 2.

Prof Mitch Schaffler:

Mechanotransduction and estrogen action

Prof Schaffler is Director of Orthopaedic Research, Mount Sinai School of Medicine, USA

Seats are limited, cost is $30 (includes breakfast). Book when you register.

08:30

SESSION 4 - Invited Speakers

Bone Strength

Chairs: Jill Cornish, Nick Fazzalari

The osteocyte - the cell within (58KB)
Findlay, D.M. and Atkins, G.J. (Australia)
Osteocytes and bone remodeling - they’re just dying to do the job (61KB)
Schaffler, M.B. (USA)
Skeletal adaptations during growth: insights from animal models (61KB)
Forwood, M. (Australia)

10:00

Refreshments - Morning Tea

10:30

SESSION 5 - Invited Speakers

Treatment - Osteoporosis

Chairs: Ian Reid, Craig Munns

Determination of absolute risk and treatment recommendations for osteoporosis (61KB)
Eisman, J.A. (Australia)
Osteoporosis in men (68KB)
Ebeling, P. (Australia)
Is there value in Ca/Vitamin D supplementation? (56KB)
Seibel, M. (Australia)

Outstanding Abstracts

CLINICAL:
Zoledronate suppresses bone turnover for at least 2 years; a randomized, acebo-controlled trial (92KB)
Grey, A., Bolland, M., Horne, A., Wattie, D., Gamble, G. and Reid, I.R
BASIC:
Transgenic expression of human FSH in female mice has an anabolic effect on bone (82KB)
Kalak, R., Allan, C.M., McTavish, K.J., Dunstan, C.R., Zhou, H., Handelsman, D.J. and Seibel, M.J.

12:30

Lunch

SANOFI-AVENTIS / PROCTER & GAMBLE SYMPOSIUM
13:00-14:00

Chair: Ego Seeman (Australia)

Keynote Address:
Differences in the mechanism of action of bisphosphonates: clinical significance and new insights from the OPTAMISE study
John Bilezikian (USA)

14:00

Concurrent Sessions:

SESSION 6A - Oral Presentations

Clinical Presentations

Chairs: Julie Pasco, Nigel Gilchrist

Prevention and treatment of corticosteroid osteoporosis with zoledronic acid (64KB)
Sambrook PN, Nash P, Ferrari V and Jones G
Effects of calcium supplementation on fracture prevention depend on patient compliance (64KB)
Zhu K, Devine A and Prince RL
Predictors of poor outcomes following osteoporotic fractures in elderly women and men: an 18 year prospective study (63KB)
Bliuc D, Nguyen ND, Nguyen TV, Eisman JA and Center JR
Post-fracture mortality in men: contributions of sex hormones and bone mineral density as risk factors (64KB)
Nguyen TV, Nguyen ND, Meier C, Center JR, Eisman JA and Seibel MJ
Substantial adverse outcomes follow non-hip non-vertebral fragility fractures (62KB)
Center JR, Bliuc D, Nguyen TV and Eisman JA
Declining incidence of osteoporotic hip fracture in Australia (62KB)
Crisp A, Dixon T, Jones G, Ebeling P and Bhatia K
Validation of the FRAX algorithm and Garvan nomogram for predicting fracture risk (268KB)
Sandhu SK, Nguyen ND, Center JR, Pocock NA, Eisman JA and Nguyen TV

SESSION 6B - Oral Presentations

Basic Presentations

Chairs: Allison Pettit, Julian Quinn

Glucocorticoid signalling through osteoblasts is essential for cranial skeletal development (214KB)
Zhou H, Mak W, Kalak R, Street J, Fong-Yee C, Zheng Y, Dunstan CR and Seibel MJ
The atypical antipsychotic clozapine reduces rat osteoblast proliferation and osteoclastogenesis at therapeutic levels
Costa JL, Smith G, Callon K, Lin JM, Watson M, Vickers M, Shepherd P and Cornish J
PYY deletion increases bone formation in mice (70KB)
Wong IPL, Enriquez R, Boey D, Sainsbury A, Herzog H, Eisman JA and Baldock PA
Blockade of ephrinB2/EphB4 signaling with in the osteoblast lineage reduces osteoblast differentiation and mineralization (62KB)
Allan EH, Pompoli S, Gooi JH, Gillespie MTG, Sims NA, Krasnoperov V and Martin TJ
Contribution of trabecular rod spatial orientation to prediction of vertebral body bone strength (63KB)
Parkinson IH, Badiei A, Stauber M, Müller R and Fazzalari NL
The osteogenic potential and contribution of muscle stem cells to bone formation and repair (63KB)
Liu R, Mikulec K, Peacock L, Morse A, Schindeler A and Little DG
Endorphins alter bone material properties by actions through dynorphin (75KB)
Baldock PA, Wong I, McDonald MM, Enriquez RF, Schwarzer C, Little DG, Sainsbury A, Herzog H and Eisman JA

15:30

Afternoon Tea

POSTER PRESENTATIONS
15:30-16:30 Attended Poster Discussion Session
Posters are on display all day Friday and Saturday.

List of Poster Presentations (116KB)

16:30

INVITED PRESENTATION

Chair: Philip Sambrook

Vitamin D endocrine system and cancer
Bouillon, R.s

17:00

ANZBMS Annual General Meeting

17:30

Sessions Close

18:00

Student Networking Function

« Thursday, 28 August Saturday, 30 August »

Saturday, 30 August 2008

08:00

Registration desk opens

08:30

SESSION 7 - Invited Speakers

New Insights into Bone Biology

Chairs: Jack Martin, Colin Dunstan

Review of computational modeling in bone biology: from intracellular signaling to tissue level (76KB)
Smith, D.W. and Pivonka, P. (Australia)
Theoretical investigation of the role of the RANK-RANKL-OPG system in bone remodeling (83KB)
Pivonka, P., Zimak. J., Smith, D.W., Gardiner, B.S., Dunstan, C.R., Sims, N.A., Martin, T.J. and
Mundy, G.R. (Australia and USA)
Cortical Bone: forgotten frontier (47KB)
Zebaze, R. (Australia)

10:00

Refreshmets - Morning Tea

10:30

SESSION 8 - Invited Speakers

Other Metabolic Diseases

Chairs: Sol Posen, Rebecca Mason

Primary hyperparathyroidism: new concepts, new insights, new guidelines (72KB)
Bilezikian, J. (USA)
Management of patients with Pagets (69KB)
Cundy, T. (New Zealand)
Treatment of rheumatoid arthritis (61KB)
Romas, E. (Australia)

12:30

Lunch

MERCK, SHARP & DOHME SYMPOSIUM
13:00-14:00

Chair: Peter Ebeling

Vitamin D – the latest evidence
Roger Bouillon (USA)
Duration of bisphosphonate therapy
Peter Ebeling (Australia)

14:00

Concurrent Sessions:

SESSION 9A - Oral Presentations

Clinical Presentations

Chairs: Christine Rodda, Kong Wah Ng

A novel disorder of type I collagen characterised by high bone mass, a mineralization defect and tendon calcification (96KB)
Cundy T, King A and Byers PH
Teriparatide-induced alkaline phosphatase and osteoblast activity in an adult with hypophosphatasia (76KB)
Gagnon C, Kalogerakis G, Jung C, Wong R, Sims NA and Ebeling PR
Peak bone mass was determined at 1 year-old: evidence from growth chart (109KB)
Wang Q, Cheng S and Seeman E
Vitamin D deficiency rickets in Australian children: an APSU study (79KB)
Munns C, Zacharin M, Rodda C, Davis E, Harris M, Batch J, Pascoe M, Fairchild J, Lafferty A, Whybourne A, Ward L, Morley, R, Garnett S, Burgner D, Geddes J, Cherian S, Mahajan D, Zurynski Y, McKay N and Cowell C
Sex-specific effects of repetitive loading on bone mass and geometry during growth (64KB)
Ducher G, Daly RM, Black J, Turner C and Bass SL
Age-related bone loss is predominantly intracortical, not endocortical or trabecular in origin (64KB)
Zebaze R, Ghasem-Zadeh A, Bohte A, Iuliano-Burns S, Boam-Tek, K, Mackie EJ, Price R and Seeman E
Serum levels of vitamin D, winter sun exposure, knee radiographic osteoarthritis, and knee cartilage loss in older adults: the Tasmania Older Adults Cohort (TASOAC) study (100KB)
Ding C, Parameswaran V, Burgess J, Cicuttini F and Jones G

SESSION 9B - Oral Presentations

Basic Presentations

Chairs: Julia Kuliwaba, Paul Baldock

BMP3 is a candidate for modulating focal bone erosion in Rheumatoid Arthritis (62KB)
Walsh NC, Karmarkar S, Manning CA, Tsuji K, Rosen V, and Gravallese EM
The calcitonin receptor on osteoclasts protects against hypercalcaemia in mice (67KB)
Turner AG, Tjahyono F, Chiu WSM, Moore AJ, Findlay DM, Morris HA, Zajac JD and Davey RA
Calcitonin attenuates the anabolic effect of PTH in vivo and rapidly upregulates sclerostin expression (70KB)
Gooi JH, Pompolo S, McGregor NE, Walker E Gillespie MT Quinn JMW, Martin TJ and Sims NA
OCIL (osteoclast inhibitory lectin) deficiency causes osteopenia (75KB)
Kartsogiannis V, Sims NA, Quinn JMW, Ly C, Cipeti M, Poulton IJ, Walker EC, Saleh H, McGregor NE, Wallace ME, Smyth MJ, Martin TJ, Zhou H, Ng KW and Gillespie MT
The role of Protein Kinase C δ in osteoclasts (144KB)
Khor EC, Davey T, Li B,Nakayama KI, Nakayama K, Zheng MH and Xu J
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease (68KB)
Walkley CR, Qudsi R, Sankaran VG, Gostissa M, Roth SI, Rodda SJ, Snay E, Dunning P, Fahey FH, Alt FW, McMahon AP & Orkin SH
Modelling recalcitrant NF1 bone repair in mice (62KB)
Schindeler A, Morse A, Godfrey C, Mikulec K, McDonald M and Little DG

15:30

Refreshments - Afternoon Tea

POSTER PRESENTATIONS
15:30-17:00 Attended Poster Discussion Session
Posters are on display all day Friday and Saturday

List of Poster Presentations (116KB)

17:00

Scientific Program Concludes

19:30

Conference Dinner

« Friday, 29 August

top

2008 ANZBMS Annual Scientific Meeting - 28-30 August 2008 - Melbourne, Australia

Program

Scientific Program

Key Speakers

Prof John Bilezikian

Prof Mitchell B. Schaffler

Thursday, 28 August 2008

Steroid Hormones and Bone

Cellular Interactions

Basic Biology

Friday, 29 August 2008

Prof John Bilezikian: Management and diagnosis of osteoporosis

Prof Mitch Schaffler: Mechanotransduction and estrogen action

Bone Strength

Treatment - Osteoporosis

Outstanding Abstracts

Clinical Presentations

Basic Presentations

Saturday, 30 August 2008

New Insights into Bone Biology

Other Metabolic Diseases

Clinical Presentations

Basic Presentations

Prof John Bilezikian:

Management and diagnosis of osteoporosis

Prof Mitch Schaffler:

Mechanotransduction and estrogen action