Rajesh
V. Thakker
University of Oxford, Oxford, UK
Dr. Raj Thakker (UK), the May Professor of Medicine
at the University of Oxford, is a consultant physician
at the Nuffield Department of Clinical Medicine and the
John Radcliffe Hospital. His career achievements include seminal studies on the genetic causes of hereditary
endocrine disorders including multiple endocrine
neoplasia type 1, X-linked hypophosphatemic rickets,
autosomal dominant and autosomal recessive forms
of hypoparathyroidism, familial hypocalcaemia with
hypercalciuria, HDR syndrome, and Dent’s disease.
His
recent functional studies address the roles of mutant
calcium sensing receptor in FHH, chloride channels
in HDR syndrome and GATA3 transcription factor in
Dent’s disease. Professor Thakker has been awarded
the European Journal of Endocrinology Prize from the
European Federation of Endocrine Societies (EFES), and
the Graham Bull Prize for Clinical Science from the
Royal
College of Physicians (UK). He is an Associate Editor
of
the Journal of Bone and Mineral Research and a member
of the Editorial Board of Endocrinology. |
Brendan
F. Boyce
University of Rochester Medical Centre,
Rochester, New York, USA
Dr. Brendan Boyce is Professor of Pathology and
Laboratory Medicine and of Orthopaedics at the
University of Rochester Medical Centre in New York.
His
primary research focus is the regulation of osteoclast
formation, activation and survival. Present studies
in his
laboratory are focused on the roles of NF-kappaB and
src tyrosine kinase in the increased bone resorption
and
decreased bone formation that characterise a number
of
bone diseases, including postmenopausal osteoporosis,
infl ammatory joint disease, metastatic bone disease
and loosening of orthopaedic implants. The excellence
of the research from Professor Boyce’s group is
widely
recognised, including the President’s Award for
Most
Outstanding Abstract at the 1997 Annual Scientific
Meeting of the American Society of Bone and Mineral
Research. Professor Boyce is currently President of
the International Society of Bone Morphometry and a
member of the Editorial Boards of the Journal of Bone
and Mineral Research and Endocrinology.
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