Day 2 of Paediatric Bone Symposium (half day only) – Stamford
Sydney Airport
Day 2 of Bone Imaging Workshop – Sydney University
1400 hours - coach departs Sydney domestic airport for transfer to
Cypress Lakes Resort, Hunter Valley
1800 hours - coach departs Sydney domestic airport, then Sydney University for transfer to Cypress Lakes Resort, Hunter Valley

Wednesday, 18 August 2004

0730 - 1800	Registration
0815 - 0830	Welcome
0830 - 1030	SESSION 1 - HORMONAL CONTROL OF BONE Chaired by: Rachel Davey & Jill Cornish
0830	Sex hormones & skeleton Sundeep Khosla
0915	Insights from ERKO models: what do they tell us about estrogen receptor function in bone? Natalie Sims
0940	Free orals: Osteoclast inhibitory lectin (OCIL) is required for normal bone remodelling in vivo and inhibits osteoblast function in vitro Akira Nakamura, JMW Quinn, NA Sims, CT Gange, H Zhou, V Kartsogiannis, EH Allan, TJ Martin, KW Ng & MT Gillespie
0950	Thrombin stimulates osteoclast differentiation by activation of protease-activated receptor-1 Sutharshani Sivaguranathan, PD Campbell, R Smith, CN Pagel, RN Pike & EJ Mackie
1000	Inhibition of breast cancer growth in bone using TRAIL therapy Lee Thai, A Labrinidis, S Hay, V Liapis, S Bouralexis, K Weldon, BJ Coventry, DM Findlay & A Evdokiou
1010	Targeting primary prevention of fracture in osteoporotic women: Geelong osteoporosis study Mark Kotowicz, MJ Henry, JA Pasco, KM Sanders, E Seeman & GC Nicholson
1020	Bone resorption and osteoporotic fractures in elderly men: the Dubbo osteoporosis epidemiology study Christian Meier, TV Nguyen, JR Center, MJ Seibel & JA Eisman
1030 - 1100	Morning tea
1100 - 1300	SESSION 2 - YOUNG INVESTIGATOR AWARDS Chaired by: David Findlay Sponsored by: Servier
1100	Identification and functional characterization of an osteoclast-derived osteoblastic factor: novel growth factor in bone Tony Phan, R Han, V Smuts, MH Zheng & J Xu
1115	Y-receptor and leptin interactions in the central regulation of bone formation and marrow fat Susan Allison, PA Baldock, A Sainsbury, RF Enriquez, M Couzens, H Herzog & EM Gardiner
1130	Gene expression in the Pagetic osteoblast Usha Bava, D Naot, KE Callon, IR Reid, R Pitto, S McCowan, T Cundy & J Cornish
1145	Controversies in calcium-sensing in bone Shaimaa Atwa, TC Brennan, AD Conigrave & RS Mason
1200	Zoledronic acid treatment does not delay the process of endochondral ossification in a rat fracture model Michelle McDonald, SK Dulai & DG Little
1215	Sesquiterpene lactone parthenolide blocks lipopolysaccharide induced osteolysis via the suppression of NF-kB activity Kirk Ho Man Yip, MH Zheng, HT Feng, JH Steer, DA Joyce & J Xu
1230	Functional responses of bone cells to stimulation by strontium Tara Brennan, MM Muir, AD Conigrave & RS Mason
1245	Secretory phospholipase-A2 (sPLA2) inhibition prevents ovariectomy-induced bone loss in adult rats Laura Gregory, WL Kelly & MR Forwood
1300 - 1430	Lunch Trade displays Posters (Odd No's)
1430 - 1630	SESSION 3 - CURRENT ASPECTS OF BONE BIOLOGY Chaired by: Eleanor Mackie & John Eisman
1430	Osteoblast differentiation Gerard Karsenty
1500	Regulation of bone development – blind genes vs functional adaptation Frank Rauch
1530	PTH and arrestins Serge Ferrari
1600	The bone remodelling space Erik Eriksen Sponsored by: Eli Lilly
1630 - 1700	Afternoon Tea
1700 - 1830	SESSION 4 - POSTER SESSION
1700	Poster rounds A (even poster numbers)
1745	Poster rounds B (odd poster numbers)
1830 - 2030	Welcome Reception (Exhibition & Poster area)

Thursday, 19 August 2004

0700 - 0800	Fun Run Sponsored by: Merck Sharp & Dohme
0800 - 1800	Registration
0830 - 1030	SESSION 5 - BODY WEIGHT, OBESITY AND BONE (Brokenback/Wattagan/Sugarloaf Rooms, Convention Centre, Cypress Lakes Resort) Chaired by: Richard Prince & Rory Clifton-Bligh
0830	Body weight and bone density Ian Reid
0900	Growth hormone, IGFs and bone: a promise yet unfulfilled Sundeep Khosla
0925	Y receptors in the central control of bone Paul Baldock
0950	Free oral: An association study of BMP4 polymorphisms in post-menopausal women shows effects on bone mass Richard Prince, L Rameshbabu, SG Wilson, IM Dick, FMA Islam & A Devine
1000 - 1030	Morning tea
1030 - 1200	SESSION 6 – CONCURRENT FREE ORALS (including concurrent keynote presentations)
	Basic: (Brokenback/Wattagan Rooms, Convention Centre, Cypress Lakes Resort) Chaired by: Mark Forwood & Gerald Atkins
1030	PTHrP as a mediator of DNA repair in cancer Matthew Gillespie, N Ilievska, S Bouralexis, RJ Thomas & TJ Martin
1040	ssential role for SIAH1A, but not SIAH2, ubiquitin ligase in bone growth and remodelling Natalie Sims, IJ Frew, JMW Quinn, CR Walkley, RA Dickins, LE Purton, DDL Bowtell & MT Gillespie
1050	Dietary omega-3 oils stimulate bone formation in vivo Howard Morris, A Moore, A Mulaibrahimovic, LG Cleland & MJ James
1100	M-CSF promotes proliferation of human osteoclast precursors but inhibits resorption by mature osteoclasts and is not necessary for resorption activity Jason Hodge, MA Kirkland & GC Nicholson
1110	Three-dimensional morphology of crack growth in cortical bone: implications for bone quality Julia Kuliwaba, KH Zarrinkalam, MAB Wallwork, B Martin & NL Fazzalari
1120	Tartrate-resistant acid phosphatase and cathepsin K promoters used to drive CRE recombinase expression in osteoclasts in transgenic mice Maria Chiu, JF McManus, AJ Notini, AI Cassady, JD Zajac & RA Davey
1130	Keynote Presentation - Genetic manipulation of human bone marrow stromal stem cells for enhanced regeneration of skeletal tissues Stan Gronthos
1030	Clinical: (Sugarloaf/Bimbadeen Rooms, Convention Centre, Cypress Lakes Resort) Chaired by: Kong-Wah Ng & Kerrie Sanders
1030	The effect on behaviour and bone mineral density of individualised bone mineral density feedback and educational interventions in premenopausal women: a randomised controlled trial Tania Winzenberg, B Oldenburg, M Riley, S Frendin, L De Wit & G Jones
1040	Playing golf is associated with increased vertebral bone size and mass in post menopausal women Shona Bass, J Cook, K Singleton, J Black & RM Daly
1050	The heavier they are, the harder they fall? Julie Pasco, MJ Henry, EN Merriman, GC Nicholson & MA Kotowicz
1100	Ethnic differences in effect of calcium supplementation on bone density in peripubertal girls in a double-blind, placebo-controlled randomised trial Christine Rodda, M Urdampilletta, J Hu, B Strauss, E Briganti & C Gilfillan
1110	Hormone replacement therapy and measures of hip strength: a co-twin analysis Lynda Paton, T Beck, C Nowson, C Margerison, L Semanick, S Kantor & JD Wark
1120	Early experience of bisphosphonate use in adolescents with osteonecrosis David Little, RR Brown, E Goergens & CT Cowell
1130	Keynote Presentation – The material and structural basis of bone strength: the anatomy of fracture prevention by remodelling suppressants Ego Seeman Sponsored by: Aventis Pharma Pty Ltd
1200 - 1330	Lunch Trade displays Posters (Odd No's)
1230 - 1315	LUNCHTIME WORKSHOP ON CLINICAL AUDITS: (Brokenback/Wattagan Rooms, Convention Centre, Cypress Lakes Resort) Chaired by: Graeme Jones Sponsored by: Merck Sharp & Dohme
	The bone protection project: an audit of in hospital investigation and management of osteoporosis following minimal trauma fracture (MTF) Chris Gilfillan
	RPAH first fracture clinic Lesley Sullivan
1330 - 1530	SESSION 7 - NEUROENDOCRINE CONTROL OF BONE (Brokenback/Wattagan/Sugarloaf Rooms, Convention Centre, Cypress Lakes Resort) Chaired by: Markus Seibel & Matthew Gillespie
1330	Genetic determinants of the spatial restriction of extracellular matrix mineralisation Gerard Karsenty
1415	Free orals: OPG mutations that cause idiopathic hyperphosphatasia impair OPG protein secretion Dorit Naot, CA Middleton-Hardie, H Cundy, IR Reid, T Cundy & J Cornish
1425	L-amino acid regulation of parathyroid hormone secretion Arthur Conigrave, H-C Mun, L Delbridge, M Wilkinson, SJ Quinn & EM Brown
1435	IL-13 inhibits osteoclast differentiation and enhances dendritic cell formation in human CFU-GM cultures Matthew Constable, JM Hodge, CJ Aitken, CM Lopez & GC Nicholson
1445	Lactoferrin receptors and signalling pathways in osteoblasts Amy Zhu, A Grey, T Banovic, K Callon, M Watson, J Bracegirdle, K Palmano, IR Reid & J Cornish
1455	Bone density relevance and interpretation in Caucasian children aged 9 – 16 years of age: insights from a population based fracture study Graeme Jones & D Ma
1505	Asymptomatic vertebral deformity as major risk factor for subsequent fractures and mortality: a 14-year prospective study Tuan Nguyen, C Pongchaiyakul, ND Nguyen, JR Center & JA Eisman
1515	Should all older people in residential care receive vitamin D to prevent falls? Results of a randomised trial Leon Flicker, R MacInnis, M Stein, S Scherer, K Mead, C Nowson, J Thomas, C Lowndes, JL Hopper & JD Wark
1525	The femoral neck is ellipsoid. Assumption of circularity introduces errors in FN volume, volumetric bone mineral density and bone strength Roger Zebaze, F Welsh, S Iuliano-Burns, A Evans, J Konstantynowicz & E Seeman
1535 - 1600	Afternoon Tea
1600 - 1740	SESSION 8 – CONCURRENT FREE ORALS (including concurrent keynote presentations)
	Basic: (Brokenback/Wattagan Rooms, Convention Centre, Cypress Lakes Resort) Chaired by: Colin Dunstan & Rebecca Mason
1600	Vitamin D metabolism in human osteoblasts Gerald Atkins, PH Anderson, K Welldon, ACW Zannettino, PD O’Loughlin, HA Morris & DM Findlay
1610	Prostaglandin E2 mediates IL-6 production by thrombin-stimulated osteoblasts Charles Pagel, S-J Song, L-H Loh, S Merlin , E Tudor, RN Pike & EJ Mackie
1620	Hydrogen peroxide accelerates human osteoclast differentiation and up-regulates thioredoxin Michelle Chacksfield, JM Hodge, CJ Aitken & GC Nicholson
1630	Expression of tenascin-w as a potential tenascin-c replacement in the skeleton of tenascin-c knockout mice Brad Morrison, A Scherberich, R Chiquet-Ehrismann, CN Pagel & EJ Mackie
1640	N-acetylcysteine inhibits human osteoclast differentiation via modulation of the thioredoxin system Nicola Zimmerman, CJ Aitken, JM Hodge & GC Nicholson
1650	Generation of a calcitonin receptor (CTR) LOXP mouse line for targeted deletion in osteoclasts Rachel Davey, JF McManus, AJ Moore, WSM Chiu, AJ Notini, HA Morris, DM Findlay & JD Zajac
1700	The effect of lactoferrin on RANKL and OPG mRNA levels in bone cells Pak Cheung Tong, D Naot, U Bava, JM Lin, M Watson, KE Callon, IR Reid & J Cornish
1710	Keynote Presentation – Interaction between bone cells and the immune system Matthew Gillespie
	Clinical: (Sugarloaf/Bimbadeen Rooms, Convention Centre, Cypress Lakes Resort) Chaired by: Geoff Nicholson
1600	Prediction of hip fracture in the elderly by fall-related factors Nguyen Dinh Nguyen, C Pongchaiyakul, JR Center, JA Eisman & TV Nguyen
1610	Genetic and environmental contributions to hip strength: in female twins aged 18 and over John Wark, L Paton, TJ Beck, L Semanick, S Kantor, R The & C Nowson
1620	The characteristics of bone fractures in Polish adolescents aged 16 - 20 years. Anthropometric, constitutional and environmental conditions Jerzy Konstantynowicz, I Bialokoz-Kalinowska, R Motkowski, P Abramowicz, J Piotrowska-Jastrzebska, J Sienkiewicz & E Seeman
1630	Balance performance, muscle strength and gait function in women: effects of genes and environment Natalie El Haber, K Hill, A-M Cassano, JS Cui, R MacInnis, JL Hopper & JD Wark
1640	Mechanosensitivity of the femoral neck in females is not increased during the adolescent growth spurt Mark Forwood, DA Bailey, TJ Beck, RL Mirwald, ADG Baxter-Jones & K Uusi-Rasi
1650	Quantitative ultrasound of the calcaneus but not biochemical markers of bone turnover are associated with fractures in frail older people with vitamin D deficiency: the FREE study Philip Sambrook, JS Chen, MJ Seibel, LM March, ID Cameron & RG Cumming
1700	Loss of femoral neck bone mass with rapid weight loss is more strongly related to baseline fat mass than change in body composition Kerrie Sanders, GK Kiroff & GC Nicholson
1710	Keynote Presentation - Structural and material basis of bone strength and its decay Nick Fazzalari
1800 - 1900	Annual General Meeting Brokenback/Wattagan Rooms, Convention Centre, Cypress Lakes
1930 - 2300	Gala Dinner, Tamburlaine Winery Sponsored by: Osteoporosis Australia

Friday, 20 August 2004

0830 - 1310	Registration
0900 - 1030	SESSION 9 - SKELETAL MALIGNANCY AND METABOLIC BONE DISEASE Chaired by: Michael Hooper Sponsored by: Novartis Oncology
0900	Treatment of advanced prostate cancer Fred Saad
0930	TNF family members and malignancy Colin Dunstan
1000	Bisphosphonate use in orthopaedic therapies David Little
1030 - 1100	Morning tea
1100 - 1310	SESSION 10 - OSTEOPOROSIS THERAPIES Chaired by: Mark Kotowitz Sponsored by: Eli Lilly
1100	Molecular mechanisms in anabolic therapy Jack Martin
1130	Wnt/LRP5 mutations and osteoporosis Serge Ferrari
1200	Treatment of osteoporosis in women – why, whom, when, what drug? Ego Seeman
1230	Monitoring osteoporosis treatment Markus Seibel
1300	Concluding remarks Ego Seeman
1310 - 1350	Lunch
1400	Coaches depart for Sydney

DISCLAIMER: Scientific program & social event details are accurate at the
time of creation and are subject to change without notice.

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